Zhu, Liangming, PhD, Professor

Department Director, Jinan Central Hospital Affiliated to Shandong University

Address: No.105 Jiefang Road, Jinan, Shandong Province, China 250012

Tel. 0531-85695429

Email: pengchongsd@sina.com

Research Interests: Clinical and basic research of lung cancer; ERAS and psychological nursing in perioperative period of thoracic surgery

Academic advisor for Master's students: Yes

Academic advisor for PhD students: Yes

Education Background

2011.09-2015.06 Shandong University, PhD in Medicine

2000.09-2003.06 Shandong University, Master in Medicine

1986.09-1991.07 Weifang Medical University, Bachelor Degree in Medicine

Work Experience

2002.12-Present  Jinan Central Hospital Affiliated to Shandong University

1993.12-2002.12  Shandong Chest Hospital

1991.07-1993.12 Shandong Taishan Sanatorium

Description of Research and Teaching

My research team focus on two fields, clinical and basic research of lung cancer、ERAS and psychological nursing in perioperative period of thoracic surgery. The clinical and basic research of lung cancer aims to improve the outcomes of patients with lung cancer diseases. The perioperative ERAS and psychological nursing research focus on understanding perioperative knowledge related to nursing learning. so as to improve nursing students’ comprehensive quality.

Research Projects

2019.05-2022.05   Relationship between SPHK1/STAT3 and clinicopathological

features of lung adenocarcinoma  Shandong university

2018.04-2022.03   Clinical study on postoperative adjuvant TKI and

chemotherapy in patients with EGFR mutant lung cancer  Shandong university

Publications

Journal articles:

1. Clinical and prognostic significance of signal transducer and activator of transcription 3 and mucin 1 in patients with non small cell lung cancer following surgery, ONCOLOGY LETTERS, 2018, 15: 4278-4288. (Correspondence Author, SCI)

2.Clinical and Prognostic Significance of MUC1 Expression in Patients with Esophageal Squamous Cell  Carcinoma after Radical Resection, Saudi Journal of Gastroenterology, 2018 , 24(3): 165-170. (Correspondence Author, SCI)

3. Mediastinum primary small cell neuroendocrine carcinoma  CONTEMP ONCOL 20(1):86-90,2016. (Correspondence Author, SCI)

4. Relationship between STAT3 signaling pathway and its target gene VEGF,VEGF-C in patients with non-small cell lung cancer Chinese Journal of Cancer Prevention and Treatment 23(12):780-785,2016. (Correspondence Author, Core)

5. Relationship Between Signal transduction and transcription factor 3 and postoperative prognosis in patients with non-small-cell lung carcinoma disease Chinese Journal of Experimental Surgery 33(8):1910-1912,2016. (Correspondence Author, Core)

6. Effect of percutaneous microwave ablation combined with radiotherapy and chemotherapy on peripheral non-small-cell Lung Carcinoma Shandong Medical Jonrnal 56(6):42-44,2016. (Correspondence Author, Core)

7. Sphingosine kinase 1 enhances the invasion and migration of non-small cell lung cancer cells via the AKT pathway ONCOLOGY REPORTS 33(3):1257-1263,2015. (The first author, SCI)

8. Clinical research on video-assisted thoracoscopic iodine tincture pleurodesis for treating malignant pleural effusion Chinese Journal of Clinical Oncology, 42(3): 167-172,2015. (Correspondence Author, Core)

9. Percutaneous microwave coagulation for treating peripheral non-small-cell lung cancer Chinese Journal of Clinical Oncology, 40(21):1314-1317,2013. (Correspondence Author, Core)

10. Down-regulation of heparanase leads to the inhibition of invasion and proliferation of A549 cells in vitro and in vivo,Acta Biochim Biophys Sin 2013, 45: 188–193. (The second author, SCI)

11. Tumor Necrosis Factor-_ Pathway Plays a Critical Role in Regulating Interferon- Induced Protein-10 Production in Initial Allogeneic Human Monocyte–Endothelial Cell Interactions, Transplantation Proceedings, 44, 993–995 (2012). (The second author, SCI)

12. The Interleukin-2 Receptor Chain (CD25) Plays an Important Role in Regulating Monocyte-Derived CD40 Expression During Anti-Porcine Cellular Responses, Transplantation Proceedings, 44, 1139–1142 (2012). (The third author, SCI)

13. Monocyte-Derived CD40 Expression Is Regulated by Interferon-r/Interferon-r Receptor-1 Pathway when Acting as a Bridge DuringTheir Interaction with T Cells and Allogeneic Endothelial Cells . Transplantation Proceedings 44,996-998(2012). (The first author, SCI)

14. Immunomodulation of Human CD8_ T Cells by Thymoglobulin In Vitro, Transplantation Proceedings, 44, 1052–1054 (2012). (The third author, SCI)

15. Inhibition of xenogenic cell-mediated immune response by a new generation of polyclonal antibodies, Chinese Journal of Organ Transplantation, 30(2):103-106, 2009. (The first author, Core)

16. CD4 T-Cell and Monocyte Interdependence During Discordant Xenoimmune Responses, Transplantation Proceedings, 40, 2764–2768 (2008). (The first author, SCI)

17. Rabbit Anti-Human Leukocyte Polyclonal Antibody Inhibits Xenogeneic Cell-Mediated Immune Responses, Transplantation Proceedings, 2008(40): 2760-2763. (The first author, SCI)

Books

Diagnosis and Treatment of Lung Cancer  Henan Science and Technology Press, Editor 3/3,2013.01

Awards and Honors

1. 2018 "Excellent Department Director" of Shandong Hospital Association

2. 2016 "Advanced Individual for Medical Service in Jinan"

3. Excellent instructor of the second National Clinical Skills Competition for College Students of Higher Medical Colleges and Universities

4. 2007"Top talents of Jinan Health Bureau"

5. 2004"Top ten technical pacesetters of young and middle-aged doctors in Jinan city"

Additional Experiences

1. Vice Chairman, Professional Committee of Tuberculosis Surgery, Shandong Tuberculosis Prevention Association

2. Member of standing committee of Thoracic tumor Branch of Shandong Anti-cancer Association

3. Member of thoracic Surgeons Branch of Shandong Medical Doctor Association

4. Vice chairman of Cardiothoracic Surgery Society of Jinan Medical Association

5.Member of the Standing Committee of minimally Invasive Lung Cancer Treatment Branch, Chinese Anti-cancer Association

6. Member of Thoracic Surgery Branch of Shandong Medical Association

7. Member of Shandong Medical Association Medical Education Branch