Li Feng, MD, Associate Professor, Deputy Physician

Neurosurgery Department, Qilu Hospital of Shandong University

Address: No. 107 Wenhuaxi Road,Huamei Building 9th floor

Jinan, Shandong Province, China 250012

Tel:18560085729

Email: lidoc@163.com

Research Interests: Basic and clinical research of nerve tumor treatment; Neural stem cells and regeneration and functional recovery after brain injury

Academic advisor for Master's students: Yes

Academic advisor for PhD students: No

Education Background

1. 2002.09-2007.06    Shandong University School of Medicine Postgraduate

2. 1997.09-2002.06    Shandong University School of Medicine Bachelor

Work Experience

1. 2015.09-present    Deputy Chief Physician and Associate Professor, Qilu Hospital of Shandong University

2. 2008.02-2015.08    Attending physician, Qilu Hospital of Shandong University

3. 2007.08-2008.02    Resident physician, Qilu Hospital of Shandong University

Description of Research and Teaching

Dr. Li joined Qilu hospital of Shandong University in 2007. He has a PhD in medicine. He was appointed as the Deputy cheif physician since September 2015.

Throughout his career, Dr. Li's research focused on neurosurgery, especially on the diagnosis and comprehensive treatment of complex and difficult tumors in the central nervous system. He is also committed to the minimally invasive treatment of central skull base tumors such as pituitary adenoma, craniopharyngioma, chordoma and meningioma, and the comprehensive treatment of trigeminal neuralgia by radiofrequency and minimally invasive surgery. He presided over two key research and development plans in Shandong Province; National Natural Science Foundation of China, Natural Science Foundation of Shandong Province, Special Project Supported by China Postdoctoral Science Foundation, First Class Project Supported by China Postdoctoral Science Foundation, and Independent Innovation Fund of Shandong University. Published 29 English papers and 19 Chinese papers in SCI.

He is Outstanding young doctor in Qilu hospital of Shandong University, outstanding young talent in Qilu Hospital of Shandong University, member of Shandong Emergency Health Expert Advisory Committee.

Research Projects

1. Mechanism of research project fund of Chinese nursingmir-27b regulating NFE2L2 pathway on NSCs proliferation and differentiation

2. MiR-27b/Nrf2 pathway regulates the role of ubiquitin-proteasome system in promoting nerve function recovery

Publications

Journal articles:

1. Anatomical Features and Clinical Significance of Radiculomuscular Artery Variants Involving the Suboccipital Segment of Vertebral Artery: Angiographic and Cadaver Studies. Clin Neuroradiol.2018 Mar;28(1):75-80.

2. Preoperative albumin-to-globulin ratio and prognostic nutrition index predict prognosis for glioblastoma. OncoTargets and Therapy.2017 Feb 8;10:725-733.

3. Tert-butylhydroquinone protects PC12 cells against ferrous sulfateinduced oxidative and inflammatory injury via the Nrf2_ARE pathway. Chemico-Biological Interactions.2017 Aug 1;273:28-36.

4. MicroRNA-27b inhibition promotes Nrf2ARE pathway activation and alleviates intracerebral hemorrhage-induced brain injury. Oncotarget.2017 Aug 7;8(41):70669-70684

5. Combined Hyperactive Dysfunction Syndrome of the Cranial Nerves_ A Retrospective Systematic Study of Clinical Characteristics in 44 Patients. World Neurosurg.2017 Aug;104:390-397.

6. Pathologic Progression, Possible Origin, and Management of Multiple Primary Intracranial Neuroendocrine Carcinomas. World Neurosurg.2017 Oct;106:1054.e13-1054.e17.

7. Secreted Protein Acidic and Rich in Cysteine Modulates Molecular Arterial Homeostasis of Human Arterial Smooth Muscle Cells In Vitro. J Mol Neurosci. 2016;60(4):509-516.

8. Nuclear factor-κB activation in perihematomal brain tissue correlates with outcome in patients with intracerebral hemorrhage，Journal of Neuroinflammation，2015,12:53(1-7)

9. NF-κB activation and cell death after intracerebral hemorrhage in patients. Neurological Sciences. 2014;35(7):1097-102

Awards and Honors

1. Outstanding young doctors in Qilu famous doctor system of Qilu hospital of Shandong University;

2. Outstanding youth in Qilu hospital of Shandong university；

Additional Experiences

Dr. Li holds various positions in clinical medicine and neurosurgery, including

1. Secretary General and Executive Director of Shandong Pain Medical Association;

2. Director of Shandong Laser Medical Association;

3. Chairman of the Youth Committee of Neurosurgery of Shandong Pain Medical Association;

4. Member of Pediatric Glioma Group of Chinese Medical Doctor Association,

5. Member of Glioma Group of Chinese Anti-Cancer Association;

6. Member of Shandong glioma cooperation group.